TOP2B - RBX1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
RBX1	ENSG00000100387	No diseases in record	No drugs in record	ubiquitin-protein transferase activity protein binding zinc ion binding ligase activity NEDD8 transferase activity ubiquitin protein ligase binding protein complex binding ubiquitin-ubiquitin ligase activity ubiquitin protein ligase activity cullin family protein binding	HRT1 (S. cerevisiae) rbx-1 (C. elegans) Roc1a (D. melanogaster)