Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
|
Orthologs
|
TOP2B
|
ENSG00000077097
|
No diseases in record
|
ETOPOSIDE
TENIPOSIDE
|
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
ATP binding
protein C-terminus binding
DNA binding, bending
enzyme binding
histone deacetylase binding
metal ion binding
protein heterodimerization activity
|
TOP2 (S. cerevisiae)
cin-4 (C. elegans)
top-2 (C. elegans)
|
IRS1
|
ENSG00000169047
|
No diseases in record
|
No drugs in record
|
signal transducer activity
transmembrane receptor protein tyrosine kinase adaptor activity
protein kinase C binding
Ras guanyl-nucleotide exchange factor activity
insulin receptor binding
insulin-like growth factor receptor binding
protein binding
1-phosphatidylinositol-3-kinase activity
SH2 domain binding
phosphatidylinositol 3-kinase binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
tRNA binding
aminoacyl-tRNA editing activity
ATP binding
isoleucine-tRNA ligase activity
|
chico (D. melanogaster)
|