TOP2B - FKBP1A

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
FKBP1A	ENSG00000088832	No diseases in record	CYCLOSPORINE EVEROLIMUS PIMECROLIMUS SIROLIMUS TACROLIMUS TEMSIROLIMUS	peptidyl-prolyl cis-trans isomerase activity signal transducer activity transforming growth factor beta receptor binding protein binding macrolide binding FK506 binding enzyme binding Hsp70 protein binding type I transforming growth factor beta receptor binding protein homodimerization activity ion channel binding SMAD binding activin binding calcium channel inhibitor activity	FPR1 (S. cerevisiae) FK506-bp2 (D. melanogaster)