TOP2B - CDK5

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
CDK5	ENSG00000164885	No diseases in record	No drugs in record	p53 binding protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity ErbB-2 class receptor binding protein binding ATP binding cytoskeletal protein binding kinase activity protein kinase binding acetylcholine receptor activator activity ErbB-3 class receptor binding ephrin receptor binding tau-protein kinase activity	CDC28 (S. cerevisiae) cdk-5 (C. elegans) Cdk5 (D. melanogaster)