MCM2 - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MCM2	ENSG00000073111	No diseases in record	No drugs in record	DNA binding DNA helicase activity DNA replication origin binding protein binding ATP binding enzyme binding histone binding metal ion binding chromatin binding single-stranded DNA-dependent ATP-dependent DNA helicase activity nucleotide binding hydrolase activity helicase activity single-stranded DNA binding 3'-5' DNA helicase activity ATP-dependent DNA helicase activity	MCM2 (S. cerevisiae) Mcm2 (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)