SMARCB1 - ERCC2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMARCB1	ENSG00000099956	malignant rhabdoid	No drugs in record	RNA polymerase I CORE element sequence-specific DNA binding p53 binding DNA binding transcription coactivator activity protein binding Tat protein binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding nucleosomal DNA binding	SFH1 (S. cerevisiae) snfc-5 (C. elegans) Snr1 (D. melanogaster)
ERCC2	ENSG00000104884	skin basal cell skin squamous cell melanoma	No drugs in record	DNA binding ATP-dependent DNA helicase activity protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity 5'-3' DNA helicase activity metal ion binding protein N-terminus binding 4 iron, 4 sulfur cluster binding protein kinase activity RNA polymerase II carboxy-terminal domain kinase activity	RAD3 (S. cerevisiae) Y50D7A.11 (C. elegans) Xpd (D. melanogaster)