POLE - MAP3K5

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)
MAP3K5	ENSG00000197442	No diseases in record	No drugs in record	magnesium ion binding protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity protein binding ATP binding protein kinase binding protein phosphatase binding protein homodimerization activity	BCK1 (S. cerevisiae) STE11 (S. cerevisiae)