TAF6 - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TAF6	ENSG00000106290	No diseases in record	No drugs in record	DNA binding protein binding protein heterodimerization activity transcription factor activity, sequence-specific DNA binding RNA polymerase II activating transcription factor binding protein complex scaffold activity chromatin binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly	TAF6 (S. cerevisiae) Taf6 (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)