PIAS2 - ABL1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PIAS2	ENSG00000078043	No diseases in record	No drugs in record	DNA binding transcription coactivator activity protein binding transcription factor binding zinc ion binding ligase activity SUMO transferase activity ubiquitin protein ligase binding androgen receptor binding SUMO ligase activity	NFI1 (S. cerevisiae) SIZ1 (S. cerevisiae) gei-17 (C. elegans) Su(var)2-10 (D. melanogaster)
ABL1	ENSG00000097007	CML ALL T-ALL	BOSUTINIB DASATINIB IMATINIB NILOTINIB PONATINIB REGORAFENIB	magnesium ion binding DNA binding actin monomer binding nicotinate-nucleotide adenylyltransferase activity protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein kinase C binding protein binding ATP binding protein C-terminus binding SH3 domain binding syntaxin binding manganese ion binding actin filament binding mitogen-activated protein kinase binding proline-rich region binding receptor binding	abl-1 (C. elegans) Abl (D. melanogaster)