PAK1 - POLE

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
PAK1 ENSG00000149269

No diseases in record

No drugs in record

protein kinase activity
protein serine/threonine kinase activity
signal transducer, downstream of receptor, with serine/threonine kinase activity
protein binding
collagen binding
ATP binding
protein kinase binding
STE20 (S. cerevisiae)
POLE ENSG00000177084 colorectal carcinoma
endometrioid carcinoma
stomach carcinoma
skin cancer
colorectal cancer susceptibility
CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
nucleotide binding
DNA binding
chromatin binding
DNA-directed DNA polymerase activity
zinc ion binding
single-stranded DNA 3'-5' exodeoxyribonuclease activity
4 iron, 4 sulfur cluster binding
POL2 (S. cerevisiae)
pole-1 (C. elegans)
DNApol-epsilon255 (D. melanogaster)