SMAD1 - SHMT1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMAD1	ENSG00000170365	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding signal transducer activity, downstream of receptor protein binding protein kinase binding transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity identical protein binding protein homodimerization activity metal ion binding protein heterodimerization activity co-SMAD binding I-SMAD binding primary miRNA binding	sma-3 (C. elegans) sma-2 (C. elegans)
SHMT1	ENSG00000176974	No diseases in record	No drugs in record	glycine hydroxymethyltransferase activity protein binding L-allo-threonine aldolase activity amino acid binding pyridoxal phosphate binding identical protein binding protein homodimerization activity serine binding	SHM1 (S. cerevisiae) SHM2 (S. cerevisiae)