VAV1 - LRRK2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
VAV1	ENSG00000141968	T-cell lymphoma	No drugs in record	transcription factor activity, sequence-specific DNA binding guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding Rac guanyl-nucleotide exchange factor activity metal ion binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	CDC24 (S. cerevisiae)
LRRK2	ENSG00000188906	No diseases in record	No drugs in record	SNARE binding glycoprotein binding actin binding GTPase activity protein kinase activity protein serine/threonine kinase activity MAP kinase kinase activity GTPase activator activity protein binding ATP binding GTP binding microtubule binding tubulin binding kinase activity Rho GTPase binding syntaxin-1 binding receptor signaling complex scaffold activity clathrin binding GTP-dependent protein kinase activity peroxidase inhibitor activity co-receptor binding identical protein binding protein homodimerization activity ion channel binding protein kinase A binding beta-catenin destruction complex binding	MEK1 (S. cerevisiae)