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KDM5A - NSD1
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
KDM5A
ENSG00000073614
AML
No drugs in record
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
zinc ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
chromatin DNA binding
histone demethylase activity
JHD2 (S. cerevisiae)
rbr-2 (C. elegans)
NSD1
ENSG00000165671
AML
No drugs in record
RNA polymerase II core promoter sequence-specific DNA binding
chromatin binding
transcription cofactor activity
transcription corepressor activity
zinc ion binding
histone-lysine N-methyltransferase activity
estrogen receptor binding
histone methyltransferase activity (H4-K20 specific)
retinoic acid receptor binding
retinoid X receptor binding
thyroid hormone receptor binding
histone methyltransferase activity (H3-K36 specific)
androgen receptor binding
SET2 (S. cerevisiae)
References
2463360