PTPN11 - XRCC6

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PTPN11	ENSG00000179295	JMML AML MDS	No drugs in record	phosphoprotein phosphatase activity protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity SH3/SH2 adaptor activity insulin receptor binding protein binding 1-phosphatidylinositol-3-kinase activity protein domain specific binding receptor tyrosine kinase binding D1 dopamine receptor binding phospholipase binding insulin receptor substrate binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity cell adhesion molecule binding peptide hormone receptor binding	PTP1 (S. cerevisiae) ptp-2 (C. elegans) csw (D. melanogaster)
XRCC6	ENSG00000196419	No diseases in record	No drugs in record	DNA binding damaged DNA binding double-stranded DNA binding ATP-dependent DNA helicase activity protein binding ATP binding protein C-terminus binding transcription regulatory region DNA binding macromolecular complex binding 5'-deoxyribose-5-phosphate lyase activity double-stranded telomeric DNA binding	cku-70 (C. elegans) Irbp (D. melanogaster)