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PTPN11 - LRRK2
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
PTPN11
ENSG00000179295
JMML
AML
MDS
No drugs in record
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity
SH3/SH2 adaptor activity
insulin receptor binding
protein binding
1-phosphatidylinositol-3-kinase activity
protein domain specific binding
receptor tyrosine kinase binding
D1 dopamine receptor binding
phospholipase binding
insulin receptor substrate binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
cell adhesion molecule binding
peptide hormone receptor binding
PTP1 (S. cerevisiae)
ptp-2 (C. elegans)
csw (D. melanogaster)
LRRK2
ENSG00000188906
No diseases in record
No drugs in record
SNARE binding
glycoprotein binding
actin binding
GTPase activity
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase activity
GTPase activator activity
protein binding
ATP binding
GTP binding
microtubule binding
tubulin binding
kinase activity
Rho GTPase binding
syntaxin-1 binding
receptor signaling complex scaffold activity
clathrin binding
GTP-dependent protein kinase activity
peroxidase inhibitor activity
co-receptor binding
identical protein binding
protein homodimerization activity
ion channel binding
protein kinase A binding
beta-catenin destruction complex binding
MEK1 (S. cerevisiae)