AMFR - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
AMFR	ENSG00000159461	No diseases in record	No drugs in record	ubiquitin-protein transferase activity receptor activity protein binding zinc ion binding protein binding, bridging ubiquitin-ubiquitin ligase activity chaperone binding ubiquitin protein ligase activity ubiquitin protein ligase activity involved in ERAD pathway BAT3 complex binding ubiquitin-specific protease binding	HRD1 (S. cerevisiae) hrdl-1 (C. elegans)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)