HIF1A - BLM

H. sapiens

SSL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HIF1A	ENSG00000100644	endometrioid carcinoma glioblastoma colorectal renal lung pancreatic	No drugs in record	transcription factor activity, transcription factor binding transcription factor activity, RNA polymerase II transcription factor binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding transcription factor binding enzyme binding protein kinase binding ubiquitin protein ligase binding histone acetyltransferase binding nuclear hormone receptor binding histone deacetylase binding protein heterodimerization activity Hsp90 protein binding sequence-specific DNA binding	hif-1 (C. elegans)
BLM	ENSG00000197299	leukaemia lymphoma skin squamous cell other tumour types	No drugs in record	bubble DNA binding p53 binding single-stranded DNA binding ATP-dependent DNA helicase activity helicase activity protein binding ATP binding ATP-dependent helicase activity four-way junction helicase activity ATPase activity annealing helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding DNA helicase activity DNA-dependent ATPase activity Y-form DNA binding	SGS1 (S. cerevisiae) him-6 (C. elegans) Blm (D. melanogaster)