SYVN1 - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SYVN1	ENSG00000162298	No diseases in record	No drugs in record	protein binding zinc ion binding ligase activity unfolded protein binding chaperone binding ATPase binding ubiquitin protein ligase activity ubiquitin protein ligase activity involved in ERAD pathway ubiquitin-specific protease binding	HRD1 (S. cerevisiae) sip3 (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)