SMAD1 - ERCC4

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMAD1	ENSG00000170365	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding signal transducer activity, downstream of receptor protein binding protein kinase binding transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity identical protein binding protein homodimerization activity metal ion binding protein heterodimerization activity co-SMAD binding I-SMAD binding primary miRNA binding	sma-3 (C. elegans) sma-2 (C. elegans)
ERCC4	ENSG00000175595	skin basal cell skin squamous cell melanoma	No drugs in record	single-stranded DNA endodeoxyribonuclease activity TFIID-class transcription factor binding damaged DNA binding single-stranded DNA binding endodeoxyribonuclease activity protein binding protein C-terminus binding protein N-terminus binding	RAD1 (S. cerevisiae) xpf-1 (C. elegans) mei-9 (D. melanogaster)