TPR - MSH2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TPR	ENSG00000047410	papillary thyroid NSCLC	No drugs in record	molecular_function chromatin binding mRNA binding nucleocytoplasmic transporter activity protein binding tubulin binding heat shock protein binding protein homodimerization activity mitogen-activated protein kinase binding dynein complex binding transporter activity protein anchor	Mtor (D. melanogaster)
MSH2	ENSG00000095002	colorectal endometrial ovarian	No drugs in record	Y-form DNA binding heteroduplex DNA loop binding double-strand/single-strand DNA junction binding DNA binding protein binding protein C-terminus binding centromeric DNA binding enzyme binding protein kinase binding guanine/thymine mispair binding protein homodimerization activity magnesium ion binding four-way junction DNA binding double-stranded DNA binding single-stranded DNA binding ATP binding ATPase activity mismatched DNA binding dinucleotide insertion or deletion binding single guanine insertion binding single thymine insertion binding dinucleotide repeat insertion binding oxidized purine DNA binding MutLalpha complex binding ADP binding nucleotide binding DNA insertion or deletion binding single base insertion or deletion binding damaged DNA binding	MSH2 (S. cerevisiae) spel1 (D. melanogaster)