PRDM1 - MSH2

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
PRDM1 ENSG00000057657 DLBCL

No drugs in record

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
methyltransferase activity
histone deacetylase binding
metal ion binding
promoter-specific chromatin binding
blmp-1 (C. elegans)
Blimp-1 (D. melanogaster)
MSH2 ENSG00000095002 colorectal
endometrial
ovarian

No drugs in record

Y-form DNA binding
heteroduplex DNA loop binding
double-strand/single-strand DNA junction binding
DNA binding
protein binding
protein C-terminus binding
centromeric DNA binding
enzyme binding
protein kinase binding
guanine/thymine mispair binding
protein homodimerization activity
magnesium ion binding
four-way junction DNA binding
double-stranded DNA binding
single-stranded DNA binding
ATP binding
ATPase activity
mismatched DNA binding
dinucleotide insertion or deletion binding
single guanine insertion binding
single thymine insertion binding
dinucleotide repeat insertion binding
oxidized purine DNA binding
MutLalpha complex binding
ADP binding
nucleotide binding
DNA insertion or deletion binding
single base insertion or deletion binding
damaged DNA binding
MSH2 (S. cerevisiae)
spel1 (D. melanogaster)