MSH2 - TGFBR1

H. sapiens

SSL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MSH2	ENSG00000095002	colorectal endometrial ovarian	No drugs in record	Y-form DNA binding heteroduplex DNA loop binding double-strand/single-strand DNA junction binding DNA binding protein binding protein C-terminus binding centromeric DNA binding enzyme binding protein kinase binding guanine/thymine mispair binding protein homodimerization activity magnesium ion binding four-way junction DNA binding double-stranded DNA binding single-stranded DNA binding ATP binding ATPase activity mismatched DNA binding dinucleotide insertion or deletion binding single guanine insertion binding single thymine insertion binding dinucleotide repeat insertion binding oxidized purine DNA binding MutLalpha complex binding ADP binding nucleotide binding DNA insertion or deletion binding single base insertion or deletion binding damaged DNA binding	MSH2 (S. cerevisiae) spel1 (D. melanogaster)
TGFBR1	ENSG00000106799	No diseases in record	No drugs in record	protein kinase activity protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity transforming growth factor beta-activated receptor activity transforming growth factor beta receptor activity, type I signal transducer activity, downstream of receptor type II transforming growth factor beta receptor binding protein binding ATP binding SMAD binding metal ion binding transforming growth factor beta binding I-SMAD binding growth factor binding	babo (D. melanogaster)