MSH2 - TRIM28

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MSH2	ENSG00000095002	colorectal endometrial ovarian	No drugs in record	Y-form DNA binding heteroduplex DNA loop binding double-strand/single-strand DNA junction binding DNA binding protein binding protein C-terminus binding centromeric DNA binding enzyme binding protein kinase binding guanine/thymine mispair binding protein homodimerization activity magnesium ion binding four-way junction DNA binding double-stranded DNA binding single-stranded DNA binding ATP binding ATPase activity mismatched DNA binding dinucleotide insertion or deletion binding single guanine insertion binding single thymine insertion binding dinucleotide repeat insertion binding oxidized purine DNA binding MutLalpha complex binding ADP binding nucleotide binding DNA insertion or deletion binding single base insertion or deletion binding damaged DNA binding	MSH2 (S. cerevisiae) spel1 (D. melanogaster)
TRIM28	ENSG00000130726	No diseases in record	No drugs in record	RNA polymerase II transcription coactivator activity DNA binding chromatin binding transcription corepressor activity protein kinase activity ubiquitin-protein transferase activity protein binding zinc ion binding ligase activity ubiquitin protein ligase binding Krueppel-associated box domain binding chromo shadow domain binding promoter-specific chromatin binding transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding	bon (D. melanogaster)