POLA2 - MSH2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLA2	ENSG00000014138	No diseases in record	No drugs in record	molecular_function DNA binding DNA-directed DNA polymerase activity protein heterodimerization activity	POL12 (S. cerevisiae) div-1 (C. elegans) DNApol-alpha73 (D. melanogaster)
MSH2	ENSG00000095002	colorectal endometrial ovarian	No drugs in record	Y-form DNA binding heteroduplex DNA loop binding double-strand/single-strand DNA junction binding DNA binding protein binding protein C-terminus binding centromeric DNA binding enzyme binding protein kinase binding guanine/thymine mispair binding protein homodimerization activity magnesium ion binding four-way junction DNA binding double-stranded DNA binding single-stranded DNA binding ATP binding ATPase activity mismatched DNA binding dinucleotide insertion or deletion binding single guanine insertion binding single thymine insertion binding dinucleotide repeat insertion binding oxidized purine DNA binding MutLalpha complex binding ADP binding nucleotide binding DNA insertion or deletion binding single base insertion or deletion binding damaged DNA binding	MSH2 (S. cerevisiae) spel1 (D. melanogaster)