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Slorth
TOP2B - MSH2
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
TOP2B
ENSG00000077097
No diseases in record
ETOPOSIDE
TENIPOSIDE
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
ATP binding
protein C-terminus binding
DNA binding, bending
enzyme binding
histone deacetylase binding
metal ion binding
protein heterodimerization activity
TOP2 (S. cerevisiae)
cin-4 (C. elegans)
top-2 (C. elegans)
MSH2
ENSG00000095002
colorectal
endometrial
ovarian
No drugs in record
Y-form DNA binding
heteroduplex DNA loop binding
double-strand/single-strand DNA junction binding
DNA binding
protein binding
protein C-terminus binding
centromeric DNA binding
enzyme binding
protein kinase binding
guanine/thymine mispair binding
protein homodimerization activity
magnesium ion binding
four-way junction DNA binding
double-stranded DNA binding
single-stranded DNA binding
ATP binding
ATPase activity
mismatched DNA binding
dinucleotide insertion or deletion binding
single guanine insertion binding
single thymine insertion binding
dinucleotide repeat insertion binding
oxidized purine DNA binding
MutLalpha complex binding
ADP binding
nucleotide binding
DNA insertion or deletion binding
single base insertion or deletion binding
damaged DNA binding
MSH2 (S. cerevisiae)
spel1 (D. melanogaster)