TOP2B - XPO1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
XPO1	ENSG00000082898	CLL	No drugs in record	RNA binding nuclear export signal receptor activity transporter activity nucleocytoplasmic transporter activity protein binding Ran GTPase binding protein domain specific binding	CRM1 (S. cerevisiae) xpo-1 (C. elegans) emb (D. melanogaster)