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Slorth
GRB2 - KRAS
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
GRB2
ENSG00000177885
No diseases in record
No drugs in record
phosphotyrosine residue binding
SH3/SH2 adaptor activity
Ras guanyl-nucleotide exchange factor activity
epidermal growth factor receptor binding
neurotrophin TRKA receptor binding
protein binding
1-phosphatidylinositol-3-kinase activity
SH3 domain binding
protein kinase binding
protein phosphatase binding
identical protein binding
insulin receptor substrate binding
ephrin receptor binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
sem-5 (C. elegans)
KRAS
ENSG00000133703
pancreatic
colorectal
lung
thyroid
AML
other tumour types
No drugs in record
GTPase activity
protein binding
GTP binding
GMP binding
GDP binding
LRR domain binding
protein complex binding
RAS1 (S. cerevisiae)
RAS2 (S. cerevisiae)
let-60 (C. elegans)
Ras85D (D. melanogaster)
References
2200765