EXO1 - LRRK2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EXO1	ENSG00000174371	No diseases in record	No drugs in record	DNA binding chromatin binding RNA-DNA hybrid ribonuclease activity exonuclease activity protein binding 5'-3' exonuclease activity 5'-3' exodeoxyribonuclease activity single-stranded DNA 5'-3' exodeoxyribonuclease activity metal ion binding flap endonuclease activity double-stranded DNA 5'-3' exodeoxyribonuclease activity 5'-flap endonuclease activity hydrolase activity catalytic activity nuclease activity hydrolase activity, acting on ester bonds double-stranded DNA binding	DIN7 (S. cerevisiae) EXO1 (S. cerevisiae) exo-1 (C. elegans) tos (D. melanogaster)
LRRK2	ENSG00000188906	No diseases in record	No drugs in record	SNARE binding glycoprotein binding actin binding GTPase activity protein kinase activity protein serine/threonine kinase activity MAP kinase kinase activity GTPase activator activity protein binding ATP binding GTP binding microtubule binding tubulin binding kinase activity Rho GTPase binding syntaxin-1 binding receptor signaling complex scaffold activity clathrin binding GTP-dependent protein kinase activity peroxidase inhibitor activity co-receptor binding identical protein binding protein homodimerization activity ion channel binding protein kinase A binding beta-catenin destruction complex binding	MEK1 (S. cerevisiae)