EXO1 - BLM

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EXO1	ENSG00000174371	No diseases in record	No drugs in record	DNA binding chromatin binding RNA-DNA hybrid ribonuclease activity exonuclease activity protein binding 5'-3' exonuclease activity 5'-3' exodeoxyribonuclease activity single-stranded DNA 5'-3' exodeoxyribonuclease activity metal ion binding flap endonuclease activity double-stranded DNA 5'-3' exodeoxyribonuclease activity 5'-flap endonuclease activity hydrolase activity catalytic activity nuclease activity hydrolase activity, acting on ester bonds double-stranded DNA binding	DIN7 (S. cerevisiae) EXO1 (S. cerevisiae) exo-1 (C. elegans) tos (D. melanogaster)
BLM	ENSG00000197299	leukaemia lymphoma skin squamous cell other tumour types	No drugs in record	bubble DNA binding p53 binding single-stranded DNA binding ATP-dependent DNA helicase activity helicase activity protein binding ATP binding ATP-dependent helicase activity four-way junction helicase activity ATPase activity annealing helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding DNA helicase activity DNA-dependent ATPase activity Y-form DNA binding	SGS1 (S. cerevisiae) him-6 (C. elegans) Blm (D. melanogaster)