EZH2 - ERCC3

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EZH2	ENSG00000106462	DLBCL	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding core promoter binding DNA binding chromatin binding protein binding protein-lysine N-methyltransferase activity histone-lysine N-methyltransferase activity chromatin DNA binding histone methyltransferase activity ribonucleoprotein complex binding histone methyltransferase activity (H3-K27 specific) primary miRNA binding promoter-specific chromatin binding	SET2 (S. cerevisiae) lin-59 (C. elegans) E(z) (D. melanogaster)
ERCC3	ENSG00000163161	skin basal cell skin squamous cell melanoma	No drugs in record	DNA binding damaged DNA binding ATP-dependent DNA helicase activity helicase activity protein binding ATP binding GTP binding protein C-terminus binding transcription factor binding ATPase activity dATP binding peptide binding 3'-5' DNA helicase activity protein N-terminus binding protein kinase activity DNA-dependent ATPase activity RNA polymerase II carboxy-terminal domain kinase activity	SSL2 (S. cerevisiae) xpb-1 (C. elegans) hay (D. melanogaster)