EIF4E - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EIF4E	ENSG00000151247	No diseases in record	No drugs in record	RNA cap binding translation initiation factor activity protein binding enzyme binding eukaryotic initiation factor 4G binding repressing transcription factor binding	CDC33 (S. cerevisiae) ife-3 (C. elegans) ife-1 (C. elegans) ife-2 (C. elegans) ife-5 (C. elegans)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)