TERT - IRS1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TERT	ENSG00000164362	melanoma glioblastoma hepatocellular carcinoma bladder skin basal cell skin squamous cell mesothelioma medulloblastoma other tumour types	No drugs in record	tRNA binding transcription coactivator binding DNA binding telomerase activity telomerase RNA reverse transcriptase activity RNA binding RNA-directed DNA polymerase activity protein binding nucleotidyltransferase activity telomeric DNA binding protein homodimerization activity metal ion binding telomerase RNA binding RNA-directed 5'-3' RNA polymerase activity	EST2 (S. cerevisiae)
IRS1	ENSG00000169047	No diseases in record	No drugs in record	signal transducer activity transmembrane receptor protein tyrosine kinase adaptor activity protein kinase C binding Ras guanyl-nucleotide exchange factor activity insulin receptor binding insulin-like growth factor receptor binding protein binding 1-phosphatidylinositol-3-kinase activity SH2 domain binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity tRNA binding aminoacyl-tRNA editing activity ATP binding isoleucine-tRNA ligase activity	chico (D. melanogaster)