POLD1 - ARAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLD1	ENSG00000062822	CRC	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding damaged DNA binding DNA-directed DNA polymerase activity protein binding 3'-5'-exodeoxyribonuclease activity enzyme binding metal ion binding 4 iron, 4 sulfur cluster binding	POL3 (S. cerevisiae) F10C2.4 (C. elegans) DNApol-delta (D. melanogaster)
ARAF	ENSG00000078061	cholangiocarcinoma lung adenocarcinoma Langerhans cell histiocytosis	No drugs in record	protein kinase activity protein serine/threonine kinase activity signal transducer activity, downstream of receptor protein binding ATP binding metal ion binding	lin-45 (C. elegans)