POLD1 - IDH2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLD1	ENSG00000062822	CRC	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding damaged DNA binding DNA-directed DNA polymerase activity protein binding 3'-5'-exodeoxyribonuclease activity enzyme binding metal ion binding 4 iron, 4 sulfur cluster binding	POL3 (S. cerevisiae) F10C2.4 (C. elegans) DNApol-delta (D. melanogaster)
IDH2	ENSG00000182054	glioblastoma	No drugs in record	magnesium ion binding isocitrate dehydrogenase (NADP+) activity NAD binding isocitrate dehydrogenase (NAD+) activity catalytic activity metal ion binding oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor RNA binding	IDP1 (S. cerevisiae) IDP2 (S. cerevisiae) IDP3 (S. cerevisiae)