POLD1 - HIP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLD1	ENSG00000062822	CRC	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding damaged DNA binding DNA-directed DNA polymerase activity protein binding 3'-5'-exodeoxyribonuclease activity enzyme binding metal ion binding 4 iron, 4 sulfur cluster binding	POL3 (S. cerevisiae) F10C2.4 (C. elegans) DNApol-delta (D. melanogaster)
HIP1	ENSG00000127946	CMML NSCLC	No drugs in record	epidermal growth factor receptor binding structural constituent of cytoskeleton protein binding clathrin binding clathrin light chain binding phosphatidylinositol-3-phosphate binding phosphatidylinositol binding glutamate receptor binding AP-2 adaptor complex binding clathrin adaptor activity protein homodimerization activity phosphatidylinositol-3,4-bisphosphate binding protein heterodimerization activity actin filament binding phosphatidylinositol-3,5-bisphosphate binding phosphatidylinositol-4,5-bisphosphate binding high-affinity L-histidine transmembrane transporter activity antiporter activity actin binding phospholipid binding transcription corepressor activity	SLA2 (S. cerevisiae) Hip1 (D. melanogaster)