POLD1 - DOT1L

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLD1	ENSG00000062822	CRC	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding damaged DNA binding DNA-directed DNA polymerase activity protein binding 3'-5'-exodeoxyribonuclease activity enzyme binding metal ion binding 4 iron, 4 sulfur cluster binding	POL3 (S. cerevisiae) F10C2.4 (C. elegans) DNApol-delta (D. melanogaster)
DOT1L	ENSG00000104885	No diseases in record	No drugs in record	DNA binding protein binding histone-lysine N-methyltransferase activity histone methyltransferase activity (H3-K79 specific) histone methyltransferase activity	DOT1 (S. cerevisiae) gpp (D. melanogaster)