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POLD1 - PTPN11
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
POLD1
ENSG00000062822
CRC
CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
nucleotide binding
DNA binding
chromatin binding
damaged DNA binding
DNA-directed DNA polymerase activity
protein binding
3'-5'-exodeoxyribonuclease activity
enzyme binding
metal ion binding
4 iron, 4 sulfur cluster binding
POL3 (S. cerevisiae)
F10C2.4 (C. elegans)
DNApol-delta (D. melanogaster)
PTPN11
ENSG00000179295
JMML
AML
MDS
No drugs in record
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity
SH3/SH2 adaptor activity
insulin receptor binding
protein binding
1-phosphatidylinositol-3-kinase activity
protein domain specific binding
receptor tyrosine kinase binding
D1 dopamine receptor binding
phospholipase binding
insulin receptor substrate binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
cell adhesion molecule binding
peptide hormone receptor binding
PTP1 (S. cerevisiae)
ptp-2 (C. elegans)
csw (D. melanogaster)