POLD1 - CDK12

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLD1	ENSG00000062822	CRC	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding damaged DNA binding DNA-directed DNA polymerase activity protein binding 3'-5'-exodeoxyribonuclease activity enzyme binding metal ion binding 4 iron, 4 sulfur cluster binding	POL3 (S. cerevisiae) F10C2.4 (C. elegans) DNApol-delta (D. melanogaster)
CDK12	ENSG00000167258	serous ovarian	No drugs in record	protein kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding RNA polymerase II carboxy-terminal domain kinase activity cyclin binding transcription factor binding transcription regulatory region DNA binding	CTK1 (S. cerevisiae) cdk-12 (C. elegans) Cdk12 (D. melanogaster)