UBE2K - PTPN11

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
UBE2K	ENSG00000078140	No diseases in record	No drugs in record	ubiquitin-protein transferase activity protein binding ATP binding ubiquitin protein ligase binding ubiquitin-ubiquitin ligase activity	UBC1 (S. cerevisiae) ubc-21 (C. elegans) ubc-22 (C. elegans) Ubc4 (D. melanogaster)
PTPN11	ENSG00000179295	JMML AML MDS	No drugs in record	phosphoprotein phosphatase activity protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity SH3/SH2 adaptor activity insulin receptor binding protein binding 1-phosphatidylinositol-3-kinase activity protein domain specific binding receptor tyrosine kinase binding D1 dopamine receptor binding phospholipase binding insulin receptor substrate binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity cell adhesion molecule binding peptide hormone receptor binding	PTP1 (S. cerevisiae) ptp-2 (C. elegans) csw (D. melanogaster)