PRKACA - IRS1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PRKACA	ENSG00000072062	fibrolamellar hepatocellular carcinoma cortisol secreting adrenal adenoma	No drugs in record	protein serine/threonine kinase activity cAMP-dependent protein kinase activity protein serine/threonine/tyrosine kinase activity protein binding ATP binding protein kinase binding ubiquitin protein ligase binding protein kinase A regulatory subunit binding	TPK1 (S. cerevisiae) TPK2 (S. cerevisiae) TPK3 (S. cerevisiae) kin-1 (C. elegans) Pka-C1 (D. melanogaster)
IRS1	ENSG00000169047	No diseases in record	No drugs in record	signal transducer activity transmembrane receptor protein tyrosine kinase adaptor activity protein kinase C binding Ras guanyl-nucleotide exchange factor activity insulin receptor binding insulin-like growth factor receptor binding protein binding 1-phosphatidylinositol-3-kinase activity SH2 domain binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity tRNA binding aminoacyl-tRNA editing activity ATP binding isoleucine-tRNA ligase activity	chico (D. melanogaster)