CBL - PCSK9

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CBL	ENSG00000110395	AML JMML MDS	No drugs in record	phosphotyrosine residue binding transcription factor activity, sequence-specific DNA binding ubiquitin-protein transferase activity signal transducer activity calcium ion binding protein binding zinc ion binding ligase activity SH3 domain binding receptor tyrosine kinase binding phosphatidylinositol 3-kinase regulatory subunit binding ephrin receptor binding ubiquitin protein ligase activity cadherin binding involved in cell-cell adhesion	sli-1 (C. elegans) Cbl (D. melanogaster)
PCSK9	ENSG00000169174	No diseases in record	No drugs in record	serine-type endopeptidase activity protein binding sodium channel inhibitor activity low-density lipoprotein particle binding receptor inhibitor activity apolipoprotein binding very-low-density lipoprotein particle binding apolipoprotein receptor binding protein self-association low-density lipoprotein particle receptor binding very-low-density lipoprotein particle receptor binding	PRB1 (S. cerevisiae) RRT12 (S. cerevisiae) YSP3 (S. cerevisiae)