MRE11 - TP63

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MRE11	ENSG00000020922	No diseases in record	No drugs in record	hydrolase activity exonuclease activity endonuclease activity protein complex scaffold activity manganese ion binding nuclease activity 3'-5' exonuclease activity G-quadruplex DNA binding single-stranded telomeric DNA binding double-stranded telomeric DNA binding telomeric DNA binding endodeoxyribonuclease activity adenylate kinase activity protein binding DNA end binding single-stranded DNA endodeoxyribonuclease activity Y-form DNA binding single-stranded DNA 3'-5' exodeoxyribonuclease activity double-stranded DNA 3'-5' exodeoxyribonuclease activity	MRE11 (S. cerevisiae) mre-11 (C. elegans)
TP63	ENSG00000073282	HNSCC DLBCL NSCLC	No drugs in record	transcription factor activity, transcription factor binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding p53 binding DNA binding chromatin binding damaged DNA binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding protein binding identical protein binding sequence-specific DNA binding transcription regulatory region DNA binding metal ion binding WW domain binding	No GO terms in record