POLE - H2AFX

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)
H2AFX	ENSG00000188486	No diseases in record	No drugs in record	DNA binding damaged DNA binding protein binding enzyme binding histone binding protein heterodimerization activity	HTA1 (S. cerevisiae) HTA2 (S. cerevisiae) His2A:CG31618 (D. melanogaster)