POLE - TAF9

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)
TAF9	ENSG00000273841	No diseases in record	No drugs in record	p53 binding DNA binding transcription coactivator activity protein binding activating transcription factor binding transcription regulatory region DNA binding protein heterodimerization activity ATPase binding C2H2 zinc finger domain binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly histone acetyltransferase activity transcription factor binding protein complex scaffold activity chromatin binding transcription factor activity, core RNA polymerase II binding	TAF9 (S. cerevisiae) taf-9 (C. elegans) e(y)1 (D. melanogaster)