PRMT1 - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PRMT1	ENSG00000126457	No diseases in record	No drugs in record	protein binding methyltransferase activity N-methyltransferase activity protein methyltransferase activity methyl-CpG binding protein-arginine N-methyltransferase activity enzyme binding protein-arginine omega-N asymmetric methyltransferase activity histone methyltransferase activity identical protein binding histone methyltransferase activity (H4-R3 specific) mitogen-activated protein kinase p38 binding	HMT1 (S. cerevisiae) prmt-1 (C. elegans) Art1 (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)