POLD1 - DICER1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLD1	ENSG00000062822	CRC	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding damaged DNA binding DNA-directed DNA polymerase activity protein binding 3'-5'-exodeoxyribonuclease activity enzyme binding metal ion binding 4 iron, 4 sulfur cluster binding	POL3 (S. cerevisiae) F10C2.4 (C. elegans) DNApol-delta (D. melanogaster)
DICER1	ENSG00000100697	sex cord-stromal tumour TGCT embryonal rhabdomyosarcoma pleuropulmonary blastoma pituitary blastoma Wilms tumour thyroid cancer other tumour types	No drugs in record	double-stranded RNA binding helicase activity endoribonuclease activity ribonuclease III activity deoxyribonuclease I activity protein binding ATP binding protein domain specific binding siRNA binding metal ion binding pre-miRNA binding	MPH1 (S. cerevisiae) dcr-1 (C. elegans) Dcr-1 (D. melanogaster)