CDK8 - FOXO1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CDK8	ENSG00000132964	No diseases in record	No drugs in record	protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding RNA polymerase II carboxy-terminal domain kinase activity RNA polymerase II transcription cofactor activity	SSN3 (S. cerevisiae) cdk-8 (C. elegans) Cdk8 (D. melanogaster)
FOXO1	ENSG00000150907	alveolar rhabdomyosarcoma	No drugs in record	RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, transcription factor binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription coactivator binding chromatin binding protein binding beta-catenin binding ubiquitin protein ligase binding sequence-specific DNA binding protein phosphatase 2A binding	HCM1 (S. cerevisiae) daf-16 (C. elegans) foxo (D. melanogaster)