TAF12 - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TAF12	ENSG00000120656	No diseases in record	No drugs in record	RNA polymerase II activating transcription factor binding DNA binding protein binding transcription factor binding TBP-class protein binding protein heterodimerization activity transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly protein complex scaffold activity chromatin binding histone acetyltransferase activity protein homodimerization activity RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly transcription factor activity, core RNA polymerase II binding	TAF12 (S. cerevisiae) taf-12 (C. elegans) Taf12 (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)