PIAS2 - TTK

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PIAS2	ENSG00000078043	No diseases in record	No drugs in record	DNA binding transcription coactivator activity protein binding transcription factor binding zinc ion binding ligase activity SUMO transferase activity ubiquitin protein ligase binding androgen receptor binding SUMO ligase activity	NFI1 (S. cerevisiae) SIZ1 (S. cerevisiae) gei-17 (C. elegans) Su(var)2-10 (D. melanogaster)
TTK	ENSG00000112742	No diseases in record	No drugs in record	protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity protein binding ATP binding protein homodimerization activity RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding chromatin binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding POZ domain binding promoter-specific chromatin binding	MPS1 (S. cerevisiae)