ACTB - PTPN11

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ACTB	ENSG00000075624	No diseases in record	No drugs in record	structural constituent of cytoskeleton protein binding ATP binding kinesin binding Tat protein binding identical protein binding nitric-oxide synthase binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding nucleosomal DNA binding	ACT1 (S. cerevisiae)
PTPN11	ENSG00000179295	JMML AML MDS	No drugs in record	phosphoprotein phosphatase activity protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity SH3/SH2 adaptor activity insulin receptor binding protein binding 1-phosphatidylinositol-3-kinase activity protein domain specific binding receptor tyrosine kinase binding D1 dopamine receptor binding phospholipase binding insulin receptor substrate binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity cell adhesion molecule binding peptide hormone receptor binding	PTP1 (S. cerevisiae) ptp-2 (C. elegans) csw (D. melanogaster)